Benefits Of Black Cohosh For Menopause: A Godsend Or A Placebo?


Ross, S.M. "Menopause: standardized isopropanolic black cohosh extract (remifemin) is found to be safe and effective for menopausal symptoms." Holist Nurs Pract (2012) Jan-Feb; 26(1): 58-61

Pockaj, B., et al. "Pilot evaluation of black cohosh for the treatment for hot flashes in women." Cancer Invest (2004) 22(4): 515-21

Low Dog, T. "Menopause: a review of botanical dietary supplements." Am J Med (2005) Dec. 19: 118

Gaube, F., "Gene expression profiling reveals effects of Cimicifuga racemosa NUTT. (black cohosh) on estrogen receptor positive human breast cancer cell line MCF-7. BMC Pharmacol (2007) Sep 20; 7: 11

Hirschberg, A., et al. "An isopropanolic extract of black cohosh does not increase mammographic breast density or breast cell proliferation in postmenopausal women." Menopause (2007) Jan-Feb; 14(1): 89-96

Raus, K., et al. "First-time proof of endometrial safety of the special black cohosh extract (Actaea or Cimicifuga racemosa extract) CR BNO 1055." Menopause (2006) Jul-Aug; 13(4); 678-91

Garita-Hernandez, M. et al. "The growth inhibitory activity of the Cimicifuga racemosa extract Ze 450 is mediated through estrogen and progesterone receptor-independent pathways." Planta Med (2006) Mar; 72(4): 317-23

Al-Akoum, M,. et al. "Synergistic cytotoxic effects of tamoxifen and black cohosh on MCF-7 and MDA-MB-231 human breast cancer cells: an in vitro study. Can J Physol Pharmacol (2007) Nov; 85(11):1153-9

Nisslein, T. and Freudenstein, J. "Coadministration of the aromatase inhibitor formestane and an isopropanolic extract of black cohosh in a rat model of chemically induced mammary carcinoma." Planta Med (2007) Apr; 73(4): 318-22

Rostock, M., et al. "Blaci cohosh (Cimicifuga racemosa) in tamoxifen-treated breast cancer patients with climacteric complaints- a prospective observational study." Gynecol Endocrinol (2011) Oct; 27(10): 844-8

Reame, N., et al. "Black cohosh has central opioid activity in postmenopausal women: evidence from naloxone blockade and positron emission tomography neuroimaging." Menopause (2008) Sep-Oct; 15(5): 832-40

Kanadys W., et al. "Efficacy and safety of black cohosh (Actaea/Cimicifuga racemosa) in the treatment of vasomotor symptoms review of clinical trials." Ginekol Pol (2008) Apr; 79(4): 287-96

Seidlova-Wuttke, D., et al. "Osteoprotective effects of Cimicifuga racemosa nd it triterpene-saponins are responsible for reduction of bone marrow fat." Phytomedicine (2012) Jul 15; 19(10): 855-60

Sethi, G., Aggarwal, B., et al. "Mending the bones with natural products." Chem Biol (2007) Jul; 14(7):738-40

Firenzuoli, F., et al. "Black Cohosh Hepatic Safety: Follow- up of 107 patients consuming a special Cimicifuga racemosa rhizome herbal extract and review of the literature." Evid Based Complement Alternat Med (2011) 2011: 821392.doi.

Naser, B., et al. "Suspected black cohosh hepatotoxicity: no evidence by meta-analysis of randomized controlled clinical trials for isopropanolic black cohosh extract." Menopause (2011) Apr; 18(4): 366-75

Teschke, R., et al. "Suspected black cohosh hepatotoxicity challenges and pitfalls of causality assessment." Maturitas (2009) Aug 20; 63(4):302-14

Teschke, R., et al. "Suspected hepatotoxicity by Cimicifuga racemosa rhizome (black cohosh, root): critical analysis and structured causality assessment." Phytomedicine (2009) Jan; 16(1): 72-84

Teschke, R., et al. "Black cohosh hepatotoxicity: quantitative causality evaluation in nine suspected cases." Menopause (2009) Sep-Oct; 16(5):956-65

Teschke, R., et al. "Black cohosh and suspected hepatotoxicity: inconsistencies, confounding variables, and prospective use of a diagnostic causality algorithm. A critical review." Menopause (2010) Mar; 17(2): 426-40

Teschke, R., et al. "Herb induced liver injury presumably caused by black cohosh: a survey of initially purported cases and herbal quality specifications." Ann Hepatol (2011) Jul-Sep; 10(3): 249-59

Mahady G., et al. "United States Pharmacopeia review of the black cohosh case reports of hepatotoxicity." Menopause (2008) Jul-Aug; 15(4 Pt 1): 628-38

Nasr, A. and Nafeh, H. "Influence of black cohosh (Cimicifuga racemosa) use by postmenopausal women on total hepatic perfusion and liver functions." Fertil Steril (2009) Nov; 92(5); 1780-2.

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